These are promising results, especially point 1, which shows patients receiving the combination therapy had an average survival time that was about 32% greater than those receiving chemotherapy alone.The study investigates the effectiveness of combining standard chemotherapy with endoscopic ultrasound (EUS)-guided phosphorus-32 (^32P) microparticle intra-tumoral implantation in patients with locally advanced pancreatic cancer (LAPC). The researchers aimed to compare this combination therapy with standard chemotherapy alone using a propensity-score weighted analysis (PSWA) to reduce selection bias.
Key Findings:
Overall Survival Improvement:
- The combination therapy group had a significantly longer restricted mean survival time (RMST) within 24 months after chemotherapy initiation. Specifically, an estimated 112 days longer than the chemotherapy-only group (459 days vs. 347 days).
Enhanced Local Progression-Free Time:
- Patients receiving the combined treatment experienced an extended local progression-free time by an estimated 112 days compared to those on standard chemotherapy alone.
Higher Probability of Tumor Downstaging:
- There was a 22.3% higher probability of tumor downstaging in the combination therapy group, suggesting better disease control.
Increased Tumor Vascularity:
- Contrast-enhanced EUS (CE-EUS) assessments showed a significant increase in intra-tumoral vascularity at 4 and 12 weeks post-^32P implantation. This suggests that the combined treatment may enhance the delivery of chemotherapy agents to the tumor by improving microvascular flow.
- Forums
- ASX - By Stock
- OSL
- Ann: Comparative Analysis Indicates Benefits from OncoSil
OSL
oncosil medical ltd
Add to My Watchlist
4.42%
!
$1.08

Ann: Comparative Analysis Indicates Benefits from OncoSil, page-4
Featured News
Add to My Watchlist
What is My Watchlist?
A personalised tool to help users track selected stocks. Delivering real-time notifications on price updates, announcements, and performance stats on each to help make informed investment decisions.
|
|||||
Last
$1.08 |
Change
-0.050(4.42%) |
Mkt cap ! $20.33M |
Open | High | Low | Value | Volume |
$1.15 | $1.15 | $1.08 | $45.62K | 40.76K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
3 | 718 | $1.08 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$1.10 | 2361 | 1 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
3 | 718 | 1.080 |
2 | 6494 | 1.075 |
3 | 26387 | 1.060 |
2 | 2961 | 1.040 |
1 | 2970 | 1.010 |
Price($) | Vol. | No. |
---|---|---|
1.110 | 9892 | 1 |
1.120 | 6617 | 1 |
1.140 | 5000 | 1 |
1.145 | 5000 | 1 |
1.150 | 6938 | 1 |
Last trade - 16.10pm 30/07/2025 (20 minute delay) ? |
Featured News
OSL (ASX) Chart |