CHM chimeric therapeutics limited

Ann: Dose finding complete in ADVENT-AML Phase 1b clinical trial, page-7

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    Good progress. Number of patients recruited is somewhere between 6-12 at this stage:

    "Trial design: The dose escalation phase will enroll a maximum of 12 patients at 2 dose levels to establish a recommended phase 2 dose (RP2D) using a BOIN design. The dose expansion will enroll up to 20 patients at the RP2D ( Fig. 1)."


    https://hotcopper.com.au/data/attachments/6559/6559513-4a0802d0520e6b1bbfd5d3edb6d1ccc5.jpg
    https://ashpublications.org/blood/article/142/Supplement%201/4863/505848/Azacitidine-Venetoclax-and-Allogeneic-NK-Cells-in

 
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