CU6 clarity pharmaceuticals ltd

Ann: Head-to-head IIT with SAR-bisPSMA, page-110

  1. 25,245 Posts.
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    "Results: In our study, 21 patients qualified for enrolment. These patients received a median of 6 treatments prior to Pluvicto. Among them, 8 (38.1%) demonstrated at least PSA50 and showed response post-treatment. Of these, 6 (75%) completed all six Pluvicto treatments, while 2 (25%) are currently undergoing treatment. Remarkably, 7 of the 8 responders (87.5%) achieved a PSA50 response after two Pluvicto doses, with all 8 (100%) reaching this marker by the third dose. Furthermore, 6 of these 8 patients (75%) exhibited a PSA90 response after the fourth dose, though 2 patients (25%) did not attain PSA90"

    The above just so anyone wondering sees the context of 87.5%, it's 87.5% of 38.1%.

    https://ascopubs.org/doi/pdf/10.1200/JCO.2024.42.16_suppl.e17026

    It'll be interesting to see how TLX591 performs in the ph3, I haven't followed them much lately but as far as I know aside from a small ph1 trial a year or so back, they haven't actually done any of their own trials so this 43 month survival is based on trials done by some other mob many moons ago?
 
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