EGCG .........negative result NPT200-11......IN PD Anle138b .......Safe and well tolerated phase 1b in PD ATH434........Ongoing
Nothing looks even close. The only one that looked interesting to me was the Promesa EGCG trial that failed the primary endpoint. Seems the EGCG dose is equal to 50 cups of green tea.Promesa is a private company.
Other trials in MSA pmc.mcbi.nih.gov/articles/PMC11055738/table/Tab1/
For the paper on the EGCG trial pmc,ncbi.nim.nih.gov/articles/PMC7327354/ Worked in monkey studies and worked in mouse studies, but had poor BBB (blood brain barrier) penetration of 2-3% and MOA is unclear. The jump from animal studies to humans does not always work out. That is why 202 was so important. Most patients were late stage so that trial was probably doomed from the start IMO.
ATH Price at posting:
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