If you are new to Neuren then this is a very informative summary by Larry Glass given in 2019, an 'oldy but a goody', one might say. If you're not new, well...go on...you know you want to. Try from about 4:30min time stamp for the unpacking of 2591's role in furnishing the brain with enough IGF-1 to have microglia function fortified and managed to a homeostatic level similar to wild type individuals that are otherwise unaffected by gene deletion or synaptopathies typical of rare diseases we now know so well.
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