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PD1-Vaxx - A Timeline
14-Jul-2020 - 3.4c
Ethics approval to commence trial.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02254667-2BE3RIII073UUCEKJ20M94KTPQ/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf
17-Jul-2020 - 3.8c
Second ethics approval received.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02256025-780RB8K0AQKAUIIRJJON4CG3U3/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf
21-Aug-2020 - 5.7c
Third ethics approval received.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02269752-3RDL40BM33LKIFVOQ54E2MQ9A1/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf
3-Sep-2020 - 5.3c
US ethics approval received.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02276976-6AMQ8C74OVU75V4APBABR3A9Q3/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf
2-Nov-2020 - 5.6c
US IND approval received
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02303391-162SH7IECSQI4EUT5EKDLNKKGF/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf1-Dec-2020 - 13.0c
First patient dosed (5 months after receiving first ethics approval.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02316433-0N0D6N2H82QT74OC5GSSE44EP5/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf17-Dec-2020 - 9.9c
First cohort enrolled.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02323466-0VVGKNPA6NGA47R56T5OKOQTHJ/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf21-Jan-2020 - 12c
Dose escalation to commence.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02332480-2E96TL9C5FJJTQ5RNTRSMOEMFE/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf12-Feb-2021 - 10c
First patient in second dose cohort dosed.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02340540-2T3QCAIAFU2UVI60MKBOVBBHVU/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf
27-Aug-2021 - 34.5c
Third dose cohort to commence.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02413211-2QPSOEULUITVCL5NFB4L5C19H0/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf4-Jan-2022 - 42.5c
P1a monotherapy dose escalation completed. Noting that in a later data release, only 14 patients from a planned 19-28 patients were included in this P1a cohort - this was not mentioned by IMU in this announcement.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02472681-117J1VITR4FQVKUO40BTOBG4JC/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf8-Aug-2022 - 28.5c
IMU presents data on the 14 P1a trial participants. Note that one patient had died due to Immune-mediated pneumonitis elicited by PD1-Vaxx.
https://cdn-api.markitdigital.com/apiman-gateway/CommSec/commsec-node-api/1.0/event/document/1410-02550704-0PTPS67BSNUFBEQFNBEA92J4NI/pdf?access_token=0007O0GNIlprvB96s1T8f7Z4fKBf1-Jun-2023 - 10c
First patient dosed in P1b combination arm. That's 18 months after the P1a was completed.
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