There's zero chance the trial will be complete by the EOY.
My guess is that the PMS P3 trail will have similar patient numbers to the Trofinetide trial, with around 200 participants.
That will take some time to recruit and complete. My guess is completion around mid 2027 with results at the end of 2027.
Ann: NEU confirms primary endpoints for Phase 3 trial in PMS, page-49
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