Merck conundrum, page-41

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    Keytruda killer Ivonescimab valued at $17B pre-approval.

    Yet PD-1/VEGF bispecifics do not activate T cells or make cold tumors hot.When PD-1/VEGF hit wall, dendritic cells prime & heat the tumor activating T cells enabling bispecifics to work.
    https://hotcopper.com.au/data/attachments/7011/7011400-6dd0655caa886357be67fce827eb731c.jpg
 
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