BZH - PYC have been granted a range of US patents over the years they have all their IP frimly locked down this is by no means the first however i think the underlining factor is early 2011 Phylogica succesfully demonstrated pre-clinical proof of concept with PYCAG5 (note the abstract below) & where persuing out-licensing agrrements with both big pharma & bio's for the candidate. However when you take J&J/Janssens deal structure initially starting out with an intraceluular target & then their November release with TBI first target of the "Ambitious neuroscience R&D program" i guess one could also assume that PYCAG5 may have played a large role in the intial deal being reached ?
“This Phylomer significantly protected neural issue in the vicinity of the lesion at four daysafter the induced head injury and decreased the extent of inflammation, increasing the potential for healing at seven days post injury.”
Dr Watt indicated the average loss of neurons from the injured region treated with Phylomer PYCAG5 was less than a third of the average loss observed for mock-treated control animals, or animals treated with a non-Phylomer peptide.
“Furthermore this particular Phylomer was associated with the largest increase in axonal sprouting relative to neuronal loss at four and seven days post-injury, which could increase the likelihood of brain tissue recovery in the damaged area.”
Anyway nothing moving fast soley on a patent being granted but it does "possibly" open the eyes into whats happening behind the scenes.
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