Structure and Drug Binding of the SARS-CoV-2 Envelope Protein in Phospholipid Bilayers
https://www.researchsquare.com/article/rs-77124/v1
The envelope (E) protein of SARS-CoV-2 assembles into a cation-selective channel that mediates virus budding, release, and host inflammation response. E blockage reduces virus pathogenicity while E deletion attenuates the virus.
These results indicate that SARS-CoV-2 E forms a structurally robust but bipartite channel whose N- and C-terminal halves can interact with drugs, ions and other viral and host proteins semi-independently. This structure establishes the atomic basis for designing E inhibitors as antiviral drugs against SARS-CoV-2.
https://www.researchsquare.com/article/rs-77124/v1.pdf
The PDF link above goes into great detail about examination of the E Protein and how to approach accessing the E Protein for an effective result with Covid 19 - If you haven't already spoken to these researches Michelle Miller - you really should!
- Forums
- ASX - By Stock
- $10 Billion Deal
Structure and Drug Binding of the SARS-CoV-2 Envelope Protein in...
-
- There are more pages in this discussion • 5,482 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add BIT (ASX) to my watchlist
|
|||||
Last
3.2¢ |
Change
0.000(0.00%) |
Mkt cap ! $28.87M |
Open | High | Low | Value | Volume |
3.3¢ | 3.3¢ | 3.2¢ | $17.40K | 542.8K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
1 | 17000 | 3.1¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
3.3¢ | 120000 | 2 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
1 | 17000 | 0.031 |
8 | 342305 | 0.030 |
5 | 1208888 | 0.029 |
4 | 468000 | 0.028 |
2 | 537000 | 0.027 |
Price($) | Vol. | No. |
---|---|---|
0.033 | 120000 | 2 |
0.034 | 100000 | 1 |
0.035 | 317251 | 4 |
0.036 | 460000 | 2 |
0.037 | 537816 | 2 |
Last trade - 16.10pm 29/07/2024 (20 minute delay) ? |
Featured News
BIT (ASX) Chart |