How much will Phase 2b and 3 cost? Is it still progressing since the aweful BIT225 assay results 'screened, not a selected hit' ?
It will cost waaaay more than what they currently have on hand
They also need more 'do-ers', lease premises, and equipment to do anything material to strengthen the Balance Sheet...so cash burn will continue to increase and weaken the Balance Sheet as Cash is the only major asset unfortunately
Poor form management, poor form
Where will they get cash from? I reckon, firstly from a Equity Raise at a price which is much much lower diluting existing shareholders and pushing any commercial deal down the road AGAIN
Here's what I perceive as the commercially weakening BIT225 results below. OOPSIE! and why can't management disclose these?...perhaps they want out at a higher price before public discovery...without transparency its not 100% known but with these guys and how they operate..its a high probability that this has been happening since 10c+ days...
38 assays and not a single hit from what they say is their best compound let that sink into your heads
ASSAY TYPE INDICATION SCREENING HIT ASSAY SOURCE 1 TSRI: CoV-2/HeLa-ACE2 SARS-COV2screened, not a selected hit Calibr 2 TB oxidative phosphorylation inhibitor M. TUBERCULOSISscreened, not a selected hit Calibr 3 TB IMAC Assay TUBERCULOSISscreened, not a selected hit Calibr 4 Crypto-C. parvum proliferation (Sterling) CRYPTOSPORIDIOSISscreened, not a selected hit Calibr 5 TB growth inhibition M. TUBERCULOSISscreened, not a selected hit Calibr 6 Intracellular nonreplicating MTB screen TUBERCULOSISscreened, not a selected hit Calibr 7 STING agonist IMMUNOONCOLOGY; ADJUVANTSscreened, not a selected hit Calibr 8 Wolbachia high-content imaging HELMINTH: ANTI-WOLBACHIAscreened, not a selected hit Calibr 9 Malaria Sporontocidals MALARIAscreened, not a selected hit Calibr 10 Zika cytopathic effect inhibition (SH-SY5Y) ZIKAscreened, not a selected hit Calibr 11 Zika Cytopathic Effect Inhibition in Vero E6 cells ZIKAscreened, not a selected hit Calibr 12 TB Tyr-tRNA synthetase inhibitor M. TUBERCULOSISscreened, not a selected hit Calibr 13 A. baumannii HUMC1 Viability serum EXTENSIVELY DRUG-RESISTANT ACINETOBACTER BAUMANNIIscreened, not a selected hit Calibr 14 Intramacrophage Mycobacterium tuberculosis TUBERCULOSISscreened, not a selected hit Calibr 15 TB DGr TUBERCULOSISscreened, not a selected hit Calibr 16 MAVS Aggregation Assay IMMUNOONCOLOGY; ADJUVANTSscreened, not a selected hit Calibr 17 A. baumannii HUMC1 Meropenem Potentiation serum EXTENSIVELY DRUG-RESISTANT ACINETOBACTER BAUMANNIIscreened, not a selected hit Calibr 18 Burkholderia pseudomallei K96243 MELIOIDOSISscreened, not a selected hit Calibr 19 Screen in Luciferase-expressing E. histolytica AMEBIASISscreened, not a selected hit Calibr 20 Viability on Pathogenic Acanthamoeba Castellanii GRANULOMATOUS AMEBIC ENCEPHALITIS (GAE)screened, not a selected hit Calibr 21 Cell Viability on Pathogenic Naegleria fowleri PRIMARY AMOEBIC MENINGOENCEPHALITIS (PAM)screened, not a selected hit Calibr 22 Shigella flexneri growth inhibition SHIGELLOSISscreened, not a selected hit Calibr 23 SigmaE-Hfq inhibition BACTERIAL INFECTIONSscreened, not a selected hit Calibr 24 Giardia 1536w Luciferase Assay GIARDIASISscreened, not a selected hit Calibr 25 LCMV Inhibitors MAMMARENAVIRUS LYMPHOCYTIC CHORIOMENINGITIS VIRUS (LCMV)screened, not a selected hit Calibr 26 tmRNA BACTERIAL INFECTIONSscreened, not a selected hit Calibr 27 Trypanosoma cruzi Assay CHAGASscreened, not a selected hit Calibr 28 THP1-ISRE-SEAP IMMUNOONCOLOGY; ADJUVANTSscreened, not a selected hit Calibr 29 Male Contraceptive Screen (Motility) HUMAN CONTRACEPTIONscreened, not a selected hit Calibr 30 Inhibitor of microbial choline metabolism GROWTH OF E. COLI ON CHOLINE-CONTAINING MINIMAL MEDIAscreened, not a selected hit Calibr 31 WRAIR LADR-luc Assay (4 day) CUTANEOUS LEISHMANIASISscreened, not a selected hit Calibr 32 Biofilm-Inhibitory of Candida Growth CANDIDIASISscreened, not a selected hit Calibr 33 ppGpp hydrolysis assay TUBERCULOSISscreened, not a selected hit Calibr 34 Block Rings and Gametocytes to Eradicate Malaria PLASMODIUM FALCIPARUMscreened, not a selected hit Calibr 35 Mtb TrpRS Biochemical Screening TUBERCULOSISscreened, not a selected hit Calibr 36 Screen against Klebsiella pneumoniae (Kp) 757 KLEBSIELLA PNEUMONIAE INFECTIONSscreened, not a selected hit Calibr 37 hRSV High Throughput Screen HUMAN RESPIRATORY SYNCYTIAL VIRUS (HRSV)screened, not a selected hit Calibr 38 DENV transmission blocking molecules (U4.4 cells) DENGUE VIRUS INFECTION (DENGUE FEVER AND HEMORRHAGIC FEVER)screened, not a selected hit Calibr
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