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"No, the 8kg of new 225 is for some lucky COVD patients, mostly...

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    "No, the 8kg of new 225 is for some lucky COVD patients, mostly in the US, and will be managed by the FDA."


    BMD, perhaps my math isn't correct? but I worked this out as-:

    The mice were dosed 12 hourly for 14 doses by oral gavage (Day 7 =
    last day):
    Group 1: 5 mice dosed with 100 mg/kg BIT225
    Group 2: 5 mice dosed with 300 mg/kg BIT225

    300mg/kg TWICE DAILY 600mg/ Kg per day
    Largest dose 600mg per KG per day , average human weight 85.9Kg for a male, 71.1Kg for a female median is 78.5 600mg/kg per day is for one kilo 600mg is .0006 kg multiply that 78.5kg = 0.0471Kg per day median weight for one person
    Would this not equate for 8Kg = 169.8 day/median doses?
 
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