2022 Development Timelines1AD - 2022 GoalsSignificantprogress...

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    2022 Development Timelines


    1AD - 2022 Goals


    Significantprogress anticipated on both existing core programs and further pipelineexpansion



    AD-214 – First in class anti-fibrotic


    • Inhaledformulation development: nebulisation feasibility, efficacy in animal model ofIPF (Q1); lung distribution imaging in healthy and disease model animals (Q1);dose finding and clinical formulation (Q2)


    • Intravenousformulation development (Q3)


    • GLP toxicologywith inhaled formulation (commences 2H22)


    • Continuing partneringdiscussions (Q1); selection of next indication




    GE Healthcare – GZMB PET imaging


    • Pre-clinicalproof of concept – milestone payment (mid-22)




    Carina Biotech – i-body enabled CAR-T cells


    • 1stexperimental results on Target #1


    • Commencei-body discovery on Target #2




    Internal pipeline and platform development


    • Initialfunctional data on i-body binders against internal Target #2 (2H22)


    • i-body2.0: newintellectual property filed (end’22)


    • 7 programs inpipeline (end’22)


    • Additionalpatent filings, grants on individual i-body enabled products

    Last edited by Dalamar: 27/03/22
 
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