I think I am pretty close with my original guess last year about CLBP being 26/27..... CHF has moved forward thanks to accelerated approval and will beat CLBP if approved.
Updated timelines:
Dec 24 -> Pediatric Actute GvHD Approval decision
2025 -> Pediatric sales for SraGvHD, Off label for adult SR GvHD
2025-> H1, Adult study srGvHD fully enrolled
2025 -> Jul to Dec 25 Accelerated approval reqest for CHF
Dec 2025 -> CLBP interim results
BIOREACTORS turned on around now
2025 H2 -> 2026 H1 -> Approval of accelerated CHF treatment and Major partnership announcement. $Multi Billion dollar market
( but extremely specialized )
2025 H2 -> Adult SrAGvHD interim results
2026 H1 -> Adult SRaGvHD Top line + resubmission
2026 H2 -> Chronic GvHD starts enrollment
2026 H2 -> Phase 3 CHF class 2 / 3 with elevated inflammation levels starts enrollment.
2026 H1 -> CLBP topline results
2026 Dec-> CLBP BLA
2027 H1 -> Adult SrGvHD approval $Billion dollar market
2027 H1 -> Chronic GvHD topline results + BLA
2027 June CLBP approval $Multi Billion dollar market
2028 H1 -> Chronic GvHD approval $Billion dollar market
2028 -> CHF Class 2 and 3 accelerated end point top line results
2029 -> CHF class 2 / 3 + inflammation approved.
________________________________________
On the to do list
Crohns
Sepsis
ARDS
Inflammatory disorders
_____________________________________________________________________________
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