Depends how much faith you put in the 'peer-review' process. Always been a bit of a boys-club circle-jerk in my experience.
Worth watching.
https://www.medrxiv.org/content/10.1101/2021.05.03.21256520v1
"In conclusion, the mRNA BNT162b2 vaccine induces complex functional reprogramming of innate immune responses, which should be considered in the development and use of this new class of vaccines."
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