50 cents On the Horizon ?, page-17

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BIT225通過阻斷Vpu離子通道的活性，它擾亂了宿主單核細胞中HIV的組裝；它的作用方式是HIV藥物的首創。​

By blocking the activity of the Vpu ion channel, BIT225 disrupts the assembly of HIV in host monocytes; its mode of action is the first of its kind.

Biotron有限公司揭示了其領先的藥物BIT225在HIV感染患者與現有抗逆轉錄病毒藥物相結合的II期試驗中的成功結果。​

Biotron Ltd. revealed the success of its leading drug, BIT225, in Phase II trials of HIV-infected patients combined with existing antiretroviral drugs.

結果表明，與抗逆轉錄病毒藥物加安慰劑相比，接受劑量為200毫克BIT225和抗逆轉錄病毒藥物的患者體內有顯著的免疫益處。​

The results showed that patients receiving a dose of 200 mg of BIT225 and antiretroviral drugs had significant immunological benefits compared with antiretroviral plus placebo.

BIT225的獨特優勢​

The unique advantages of BIT225

目前的抗逆轉錄病毒藥物在清除HIV-1病毒方面非常有效。​

Current antiretroviral drugs are very effective in clearing HIV-1 viruses.

然而，這些抗逆轉錄病毒藥物並不清除細胞中的病毒儲存庫。​

However, these antiretroviral drugs do not clear the virus reservoir in the cell.

BIT225是一種小分子療法，攻擊巨噬細胞中生長的HIV-1。​

BIT225 is a small molecule therapy that attacks HIV-1 grown in macrophages.

試驗中的資料與目標一致，在BIT225治療的患者中，HIV-1病毒被從這些關鍵的儲存細胞中根除。​

The data in the trial was consistent with the goal, and HIV-1 virus was eradicated from these critical storage cells in patients treated with BIT225.

「HIV感染者必須終身服用藥物以控制病毒。​

"HIV-infected people must take medication for life to control the virus.

「這項試驗首次表明，可能有一種方法可以清除一部分主要的細胞儲層。​

"This test shows for the first time that there may be a way to remove some of the major cell reservoirs.

「這是治癒HIV-1感染的最終目標邁出的重要一步。」​

"This is an important step in the ultimate goal of curing HIV-1 infection."

正在進行的試驗資料分析​

Ongoing test data analysis

正在進行的試驗資料分析試驗，旨在評估三個月劑量BIT225聯合抗逆轉錄病毒藥物治療初發HIV陽性患者的安全性和抗病毒活性。​

An ongoing trial data analysis trial designed to assess the safety and antiviral activity of a three-month dose of BIT225 in combination with antiretroviral drugs in the treatment of HIV-positive patients.

對試驗資料的分析正在進行中。​

Analysis of the test data is ongoing.

Biotron旨在在2018年底或2019年初在科學會議提供詳細資料，或為和潛在的商業夥伴提供。​

Biotron aims to provide detailed information at the scientific conference at the end of 2018 or early 2019, or for potential business partners.

這家公司的股票在交易日內上漲了121%，達到4.2美分。​

The company's stock rose 121% to 4.2 cents during the trading day.

BIT225的分子式​

Molecular formula of BIT225