CYP cynata therapeutics limited

9 Sept Interview BioInformant Dr Macdonald, page-7

  1. 1,311 Posts.
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    Hi @holiday,

    Please see below graph from the most recent investor presentation. It shows a survival of these last three animals till just past the 80 day mark. Somehow I do recall 83 days but I can't remember where I've read it:

    20170914_223112.png

    https://www.google.com.au/url?sa=t&...ggcMAA&usg=AFQjCNEsb7I2XoRQXNIqBHzU0mpwHbZEcQ

    Given that the life expectancy of a "lab mouse" is between 1-3 years (365-1,095), 30-50 days is quite substantial.

    http://animals.mom.me/mouses-lifespan-captivity-3962.html
    https://www.terminix.com/pest-control/mice/life-cycle/


    Here is the link to the final report you were referring to:

    http://m.asx.com.au/m/index_terms.xhtml?nextUrl=/asxpdf/20170206/pdf/43fszmr0fw758j.pdf

    "As expected, in the groups in which GvHD was not induced (gamma irradiation controls, CYP-001 single dose controls and CYP-001 dual dose controls), all animals remained healthy for the full 100-day study period, indicating that CYP-001 treatment did not adversely affect these animals. In animals in which GvHD was induced, the control animals survived for a median of just 24.5 days. However, treatment with CYP-001 markedly prolonged survival with the median survival time being 48 days and 57 days, respectively, in recipients of a single dose or dual doses of CYP-001. The differences between each CYP-001 group and the control group were highly statistically significant, showing that treatment with CYP-001 doubled, at least, the survival time of the treated animals."
    Last edited by pfeifer1982: 17/09/17
 
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