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A little help from CEO Novo Nordisk, page-12

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    Interesting read regarding overdosing on Ozempic, its not cheap either.

    Ozempic overdoses: data reveals Australians sent to emergency after misuse of diabetes drug | Health | The Guardian

    Ozempic overdoses: data reveals Australians sentto emergency after misuse of diabetes drug

    Exclusive:NSW poisons information centre received more than 120 calls related to thediabetes drug in a year, 83% of them about medication errors

    Patientshave been referred to hospital emergency departments after unintentionallytaking a higher dose of Ozempic than prescribed, data obtained by GuardianAustralia has revealed.

    The drugsemaglutide, sold under the brand name Ozempic in Australia, is subsidisedunder the pharmaceutical benefits scheme for the treatment of type 2 diabetes.

    Butdoctors also prescribe it “off label” for weight loss for those living withobesity, costing those patients more than $130 a month. It is usuallyadministered once a week via an injection pen.

    Datafrom Australia’s largest poisons information centre, in NSW, revealed that, inthe year to the end of October 2023, more than 120 calls were made to thecentre related to semaglutide. Of these, 83% were due to medication errors,including an individual taking an incorrect dose, administering the medicationincorrectly, or the medication being taken by the wrong person.

    Meanwhilethe Victorian Poisons Information Centre told Guardian Australia that in the 24months to the end of October 2023 the service had received 82 calls related toOzempic or semaglutide.

    Seven ofthese calls led to the caller being referred to an emergency department orurgent care centre for further monitoring, due to complications or adverseeffects resulting from unintentionally administering higher doses thanprescribed.

    But 10%of the calls to the Victorian service were in relation to intentionalmedication misuse.

    “Patientsreported to have used friend’s or family member’s medication for the purpose ofweight loss, or intentionally used their own prescribed medications at higherdoses than prescribed, with the goal of weight loss,” a spokesperson forAustin , which manages the service, said. The primary reason for most (74%) of the calls was unintentional medication administration errors.

    Each“pen” of Ozempic contains multiple doses, with one dose taken a week.

    “It isnot uncommon for a patient to accidentally inject the entire contents in thepen – up to four times the intended dose,” the spokesperson said. High-profile celebrities and socialmedia influencers touting Ozempic for weight loss of the drug, despite warnings about a lack of longterm data around side effects and efficacy.

    The and doctors are being advised not to write prescriptions for the drug to new patients. Meanwhile pharmacists have been told to prioritise any supply to diabetes patients.

    A the journal of the Royal Australasian College of Physicians, found increasing poison centre calls regarding semaglutide are associated with publicity of the drug as being a weight loss agent.

    The paper concluded a high number of dosingerrors “signals a need for clear dosing advice from prescribers andpharmacists, particularly to patients who may be unfamiliar with injectabledosing devices”. The supply shortage of semaglutide is a global issue,prompting people to illegally seek out counterfeit versions of the drug.Use , with patients suffering from serious side effects including seizures.

    A spokesperson for drugs regulator theTherapeutic Goods Administration (TGA) said counterfeit semaglutide productscoming into Australia have been stopped at the border and “not released to theconsumer”.

    “The TGA is not aware of any of these reportedproducts entering Australia,” the spokesperson said. “The TGA has not receivedany Australian reports of adverse events for Ozempic that suggest a counterfeitproduct was involved.”




 
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