I guess they just want to prove that laninamivir octanoate is...

I guess they just want to prove that laninamivir octanoate is save even for chronic asthma patients ?

http://www.theflyonthewall.com/permalinks/entry.php/BOTAid1922083/BOTA-Biota-initiates-additional-clinical-trials-of-laninamivir-octanoate


Biota Pharmaceuticals announced that it has commenced dosing in two Phase 1 clinical trials of laninamivir octanoate, its long-acting neuraminidase inhibitor being developed for the treatment of influenza. One of the Phase 1 clinical trials is a single center, randomized, double-blind, placebo-controlled, single ascending dose study in which the safety and pharmacokinetics of LANI, administered by inhalation via the TwinCaps dry powder inhaler, will be assessed in adults with mild to moderate chronic asthma. The study is designed to enroll up to 32 subjects. The second Phase 1 clinical trial is a thorough QT/QTc study designed to evaluate the effect of therapeutic and supra-therapeutic doses of LANI on cardiac ventricular repolarization, specifically the QT-interval, in healthy volunteers. The study is a single center, parallel design, placebo- and positive-controlled, double-blind, randomized trial. This trial is designed to enroll 168 subjects. Both studies are being conducted to support the requirements of a New Drug Application for LANI. The company expects top-line results from both of these clinical studies in the first half of 2014.