Here are two other references from the Berlin and Munch Heart...

Here are two other references from the Berlin and Munch Heart Centres. They both discuss calcification in the ADAPT Tissue and the company is stating that there has been no calcification in any patient for over 10 years ??

Histological examination of explanted tissue-engineered bovine pericardium following heart valve repair Oliver Deutsch 1 2, Frido Bruehl 3, Julie Cleuziou 2 4, Anatol Prinzing 1 2, Anna Melissa Schlitter 3, Markus Krane 1 2, Rüdiger Lange 1 2
Conclusions: Our data suggest that the tissue-engineered CardioCel patch is initially tolerated in the valvular position in the majority of patients. However, we also experienced graft failures that showed degeneration with fragmentation of the collagen matrix and even 2 cases with focal calcification evident from the histopathological analysis.

ADAPT-treated pericardium for aortic valve reconstruction in congenital heart disease: histological analysis of a series of human explantsSarah Nordmeyer 1, Johanna Kretzschmar 1, Peter Murin 2, Mi-Young Cho 2, Rudi Foth 3, Uwe Schlichting 4, Felix Berger 1, Stanislav Ovroutski 1, Joachim Photiadis 2, Matthias Sigler 3Results: Superficial endothelialization was demonstrated in all patients by immunohistochemical analysis. Nine specimens showed mild inflammatory cell infiltration (G1) (G2: n = 3). Significant appositional growth on top of the patch due to addition of fibroblasts and extracellular matrix components, was seen in all specimens (G1: n = 1; G2: n = 7; G3: n = 4). Ten of 12 samples with implant times of 23 months or longer revealed calcifications (G1: n = 6; G2: n = 3; G3: n = 1). Two specimens with the shortest implant times (11 and 20 months) showed no calcifications (G0). Thrombus apposition with granulocyte infiltration was demonstrated in the specimen of the patient with endocarditis.
Conclusions: In our cohort, all CardioCel patches used for aortic valve repair in patients with congenital heart disease demonstrated appositional growth of fibroblasts and extracellular matrix components, and calcification after an implant time of at least 23 months.