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and further, page-45

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    The priority of points in this release does seem to put cessation last :
    "– the impact of nadolol on biomarkers of airway inflammation, β-arrestin pathway activation and abnormal mucus production;
    – the safety and efficacy of nadolol as an aid to smoking cessation in patients with increased cough and sputum (phlegm) production who have repeatedly failed to quit; and
    – the correlation of biomarkers of airway healing with cigarette smoking reduction or cessation, in order to optimise the nadolol regimen and patient selection for planned phase III clinical trials."
 
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