A few things I gleaned from listening to the Q & A in the CureSHANK webinar this morning:
- The dose used in the trial (which is the same dose that will be used going forward) represents, for a 25kg patient, the equivalent of 5cc (1 teaspoon), taken twice daily.
- While an open label trial design was used in the Phase 2 study, it is expected that Phase 3 will be placebo-controlled.
- Safety was the broad reason for the exclusion of 5 patients after screening.
- Participants in the Phase 3 trial will be excluded from the pivotal Phase 3 trial as neither they nor their parents will be treatment- naïve. However, it is hoped that they can be included in the Phase 3 open label extension component of the trial.
- While not yet decided, it is probable that the pivotal trial will be restricted to the same age group as the Phase 2 trial (3-12 years). However, the company remains committed to extending treatment to all age groups and an additional trial in adolescents is a possibility.
- Geography for the trial is still to be determined.
- The last question was whether it was possible that NNZ-2591 might be applicable to syndromes other than PMS. The founder of CureSHANK was thrilled to hear that NNZ-2591 was being tested in other indications as well and might potentially be a therapeutic used across multiple neurodevelopmental rare diseases.
- Forums
- ASX - By Stock
- NEU
- Ann: 2023 Results webinar
Ann: 2023 Results webinar, page-125
- There are more pages in this discussion • 6 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add NEU (ASX) to my watchlist
(20min delay)
|
|||||
Last
$23.97 |
Change
3.260(15.7%) |
Mkt cap ! $3.060B |
Open | High | Low | Value | Volume |
$23.00 | $24.00 | $21.60 | $27.11M | 1.181M |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
2 | 942 | $23.95 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$23.97 | 27 | 1 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
2 | 942 | 23.950 |
1 | 2092 | 23.900 |
1 | 3000 | 23.850 |
1 | 5000 | 23.830 |
1 | 4511 | 23.740 |
Price($) | Vol. | No. |
---|---|---|
23.970 | 27 | 1 |
23.990 | 300 | 1 |
24.000 | 20376 | 11 |
24.010 | 1000 | 1 |
24.030 | 649 | 1 |
Last trade - 16.10pm 27/05/2024 (20 minute delay) ? |
|
|||||
Last
$24.00 |
  |
Change
3.260 ( 16.0 %) |
|||
Open | High | Low | Volume | ||
$22.98 | $24.00 | $21.60 | 310545 | ||
Last updated 15.59pm 27/05/2024 ? |
Featured News
NEU (ASX) Chart |