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Ann: 36-Month Results of Phase 3 Trial in Chronic Low Back Pain, page-183

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    What is Degenerative Joint Disease?

    Degenerative joint disease, or osteoarthritis, is the most common type of arthritis. While this condition can occur in any joint, it usually affects the hands, knees, hips or spine.

    This disease is common because wear and tear on the joints over time can cause cartilage to break down. This can happen to anyone but typically occurs in older adults. The degeneration of cartilage means that bones lose their cushioning. They are then vulnerable to rubbing against one another within the joint. As a result, the joint area becomes inflamed and painful, leading to a decrease in mobility. In addition, bone spurs, or pieces of bone, may form around the joint. Ligaments and muscles may also become both weaker and stiffer as arthritis worsens.

    https://rothmanortho.com/stories/blog/what-is-degenerative-joint-disease-3883

 
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