>ANN 31 May 2022- first patient recruited to trial
>ANN 24 July 2023- 72nd patient randomized into the trial to complete the number needed for the part 1 group
>ANN 24 July 2023- trial operating in 70 sites around the world
>70 sites needed 14 months to get the first 72 patients= average recruitment rate about 1 patient per site per year.
>Final size of trial= 286 patients. trial needs 214 more. Without adding more sites/hospitals, at current progress rate it requires 3 more years. takes this to mid 2026.
>Then add 2 years to that once the last patient randomised to trial because patients have 2 years on trial to get to final endpoint. takes this to mid 2028
>then add on say 6-9 for regulartory approval. Takes this to early or mid 2029.
BUT that's if they stuck with 70 sites. get more sites, speed up the trial. If you know how many more sites are to be opened (haven't seen that information) then should be able to work out when trial could finish using the assumption of 1 patient per site per year.
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