Details for the OTS 2021 video poster presentation are as follows:
Title:"Cell Penetrating Peptides Facilitate the Delivery of Precision Medicines to the Brain and Spinal Cord for the Treatment of Neurological Disease"Abstract #: 205
Lead Author: Ianthe Pitout, PhD, PYC Therapeutics
Key Highlights:
- PYC's cell penetrating peptide – phosphorodiamidate morpholino (CPP-PMO) technology has the potential to solve the significant delivery challenge facing the development of precision drugs that are required to penetrate central nervous system (CNS) tissues.
- PYC's CPP-PMO reporter demonstrated dose-dependent delivery and antisense effects in tissues deep in the mouse brain, including motor cortex, striatum, corpus callosum, midbrain and the spinal cord.
- Superior delivery and an excellent safety profile of the CPP-PMO in preclinical models could translate to a strong probability of clinical success, and ultimately the creation of truly differentiated and meaningful medicines for patients with significant unmet need.
This poster presentation can be accessed on demand throughout the meeting by conference attendees on theOTS 2021 Annual Meeting website, or on PYC's website in the Posters and Publications section of thePipelinepage.
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