Looking at those results from the Lateral Flow testing with DCN Diagnostics - Anteos 200nm kit could become the gold standard for all pregnancy tests
a) AMG™ Coupling Kit, 200 nm Magnetic Particles Following the release of the 200nm kit, Anteo engaged US based DCN Diagnostics, a leading, globally recognised company for the commercialisation of high-performance, rapid assay systems, to evaluate the performance of the kit in a lateral flow assay. Lateral flow assays are commonly used for applications such as pregnancy testing and are being developed for an increasingly wide range of other tests. The study compared the performance of the Mix&Go activated magnetic particles to covalently conjugated magnetic particles in a lateral flow assay that detects human Chorionic Gonadotropin (hCG). This hormone is used to detect early stage pregnancy and is a well- known and tested model system. The conclusions of the study were:
1. The Anteo Mix&Go based hCG assay is 5 times more sensitive than the covalently conjugated magnetic particle based test using the same critical reagents.
2. The hCG assay using the Anteo Mix&Go particles used half the amount of antibody to achieve better sensitivity than the covalently conjugated particles.
3. The variability of the Anteo Mix&Go based hCG assay is lower than the covalently conjugated hCG assay. There is also less non-specific binding with the Mix&Go particles.
4. The Anteo Mix&Go particles come fully activated and are ready for the antibody conjugation. The covalent conjugation procedure requires steps to wash and activate the particles before the addition of the antibody. The Mix&Go procedure takes less time with fewer steps than the covalent conjugation procedure.
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