Ann: Avecho to present at NWR Virtual Healthcare Conference, page-23

A newly published Thai study suggests that CBD can be beneficial when used for chronic insomnia.

The randomized, double-blind, placebo-controlled, crossover pilot study in 45 chronic insomnia patients tested 1 mg/kg MCT-CBD oil, administered sublingually, for a 4 week period, followed by a 3 week washout period and a subsequent 4 week placebo phase.

Sleep architecture with N1, N2, N3, and rapid eye movement, sleep quality, daytime sleepiness and quality of life were investigated.

Polysomnography revealed that total sleep time, sleep onset latency, wake time after sleep onset, and arousal index were significantly improved compared with placebo, while sleep structure remained unaltered. Additionally, actigraphy showed a substantial improvement in total sleep time, sleep efficiency, and sleep onset latency. The results of the self-reported sleep measures – the Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, and EQ-5D-5L questionnaire – were also found to be better than placebo (p<0.05).

It was concluded

Continuously sublingual CBD treatment could improve sleep duration, sleep maintenance, sleep induction, quality of life, and daytime sleepiness without altering the sleep architecture in patients with chronic insomnia. No evidence of serious side-effects was found.

http://jmatonline.com/index.php/jmat/article/view/13952#