Not quite apples and apples drainer. Cu6 was dosing at suboptimal levels as a single agent and achieving said response. Zan was in combo at a dose they deemed at most efficacious.
cu6 want to dose cumulatively 48GBq vs what they got at undetectable, which is 16GBq. This is 33% less than what they're looking to dose as their desired dosing schedule.
With that said, achieving a CR in a terminal patient with multiple lines of treatment is a great response. Unfortunately still not within a scope of approval development plans.
Ann: Bisantrene Phase 2 AML Trial Successful Concludes, page-49
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