Looks like a couple of months delay in starting recruitment and the screening process is probably taking a bit longer than expected due to having fairly tight criteria and multiple screening stages. Eligibility looks to be running below 10% of those being screened so based on this it will be a few more months before full recruitment of the 219 is reached for the initial group. With this type of trial, participant screen will be very important, a bit more time invested here is a good thing in my opinion.
Ann: Chair's Address and CEO Presentation, page-6
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