Targeted oncology is where you have a drug that has a molecular target (say an antibody to Her2). This is different to traditional chemotherapeutic oncology where you are poisoning the cancer in the hope the cancer is a little more sensitive to the chemo drug than the patient.
Precision Oncology is where you examine the patient's cancer for the mutations that caused that particular cancer and then choose targeted agents to match the precise sensitive of the cancer. For example, if you test the cancer and give the patient low dose Bisantrene to only those patients that are over expressing FTO that is Precision Oncology. If you just give low dose Bisantrene to all patients with melanoma that is Targeted Oncology, and if you give high dose Bisantrene to breast cancer patients that is Chemotherapeutic Oncology.
Here is an article in Nature explaining to a general audience what Precision Oncology is about.
https://www.nature.com/articles/d41586-020-02673-y
Ann: Change in substantial holding, page-70
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