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Ann: Change in substantial holding, page-79

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20/12/24

16:04

Post #: 77142297
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Originally posted by RCJones: ↑

Hey Cuprum, I had the same question the other day on one of the other threads. I too would like to get some objective opinions on that path also. But, unfortunately there's a lot of cabbage and cows**t to sift through on this forum at times. The best I can come up with so far;

We know back in 2022 Antisense released the results on a Phase IIa clinical trial involving patients with relapsing-remitting MS, where ATL1102 demonstrated a reduction in disease. There was a 54% decrease in the cumulative number of new active brain lesions compared to placebo.

If the company was to change direction today and start focusing on MS, what would the timeline be picking up from the Phase IIa?

Phase IIb - 2 to 3 years

Phase III trials - 3 to 5 years

Safety studie - 1 to 2 years

Regulatory approval - 1 to 2 years

Market prep - 1 to 2 years

Total - 7-8 years (all going well)

or

ATL1103 with Acromegaly?

Thoughts?

Expand

They would Partner with big Pharma now that they have the tox completed
Acromegaly will also be Partnered

Waiting for more data from the failed trial.. for other indications …

PER Price at posting: 0.8¢ Sentiment: Buy Disclosure: Held
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Ann: Change in substantial holding, page-79

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