LTP ltr pharma limited

Ann: Commercial Update and Regulatory Progress, page-333

  1. 25,970 Posts.
    lightbulb Created with Sketch. 48
    "there seems to be plenty of evidence that Pfizzer did get this working via nasal delivery:https://www.cbc.ca/news/science/viagra-in-nasal-spray-1.246938"

    OK that was an article from 25 years ago.

    "A company official would not discuss how far advanced its research was. There was no guarantee, she says, that the inhalable version would prove effective or actually hit the market. She says more data and research are required."

    After 25 years I'm pretty sure they would have brought it to market of they got it working.

    "https://pubmed.ncbi.nlm.nih.gov/11249556/" says nothing about nasal administration.

    "*word disallowed by google (Viagra, Pfizer, Inc.) is a new orally effective therapy for the treatment of men with erectile dysfunction (ED). It is a specific and selective inhibitor of phosphodiesterase Type 5 (PDE5), an enzyme which is an important modulator of smooth muscle relaxation in the corpus cavernosum. In the presence of a sexual stimulus, inhibition of PDE5 results in improved smooth muscle relaxation within the sinusoids of the corpus cavernosum and the penile arteries. This results in improved erections in men with ED. In clinical trials, *word disallowed by google has been found to be effective in improving the erections of large numbers of men with ED secondary to a range of causes. The presence of PDE5 in other tissues such as vascular smooth muscle results in side effects such as headache, flushing, indigestion and nasal congestion. These side effects are dose-dependent and well-tolerated. The introduction of *word disallowed by google in many countries around the world has revolutionised the assessment and treatment of men with ED."


    "I know Director12 and Greedy want to up this stock..."

    Really? I want the stock I'm invested in to go up? Say it isn't so!


    "Is it the case that the Spontan patent deals with the issues identified in the earlier studies and if so how?"

    Well you're the lawyer, you'd have a better idea on how access those documents than I would.
 
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