It is with out doubt many including myself anticipated the possibility of early results, lesson learnt. SI and team have a better understanding of the time line than we do.
Why has it taken longer than we have expected ?
I think it possible that it is a combination of many things including trial design . A lot to get done in the first 3 days before enrollment and treatment, any delay in the first 2 days would exclude them from this trial . I would also think that caution would play a part.
I also would not be surprised if we may be testing Remestemcell-L with different manufacturing technology. For example, starting with what we had on hand then going to the new 3D manufacturing capabilities and then possible using fresh to finish the trail. If we are to treat large numbers , this is the type of data that will be required.
Good luck all
Ann: COVID-19/GVHD Update, Quarterly Report and Appendix 4C, page-230
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