Ann: Cynata Commences DFU Clinical Trial, page-9

I am also somewhat surprised that this test should take A FULL YEAR?!? Comments welcome.

He doesn't say it will - just currently expects. Could be less, could be more. Consider how long MEND has taken.

I'm trying to see CYP's time frames in context. A full year is exactly half of the shelf life of cells produced and placed into cryostorage (that detail was in an OA paper recently posted to this forum by pfeifer - though that wasn't why he posted it or what he highlighted - I think pfeifer was just posting good info on the OA trial with Hunter). And it costs CYP quite a bit to get those cells produced because they have to be produced under GMP conditions - and usually Waisman has done it - but CYP was never Waisman's only customer.

The amount CYP paid for Waisman to produce the last set of cells came to light because pfeifer found a reference to an approval from a reagents board - where the approval was for over a million dollars for cells and I presume cell production services.

Cells produced go off in two years (they probably don't in fact - but the FDA deems they do - so the effect is the same - they can't be used) and cost over a million dollars (there may have been more than one batch run) and cell trials (even for a quick indication like DFU) take about a year. That's context, in my opinion.

Every year taken to get through clinical trials is a year that is not available for commercial sales in the life of the patent. That's context too, in my opinion.

CYP management hasn't exactly belabored CYPs weaknesses - I suppose we shouldn't expect them too. But when Ross stresses how frugal (there is a time cost - the time comes off the patent back end) he has been or how a gold mine fell in our lap because we didn't have to fund a trial - its worth thinking in terms of actual numbers and dollars because that is what Ross gets paid in whether CYP ever shows a profit or not.

I did not buy CYP shares because I wanted to make a charitable donation to science (taking CYP cells through clinical trials and not to commercialisation would make such a contribution to science) or to Ross. I wanted a return on investment.