The numbers are good. If you go & look at some post hoc analysis of Cana, there was a broad range in reduction of UACR dependent on starting baseline.
The subgroup in DKD DMX-200 trial 500mg/L or greater achieved a 37-38% reduction in UACR. Compare that to the above of 31% at week 26 with a cohort of >300mg/L. We know from the CREDENCE trial that UACR & eGFR decline & then plateau at 26 weeks.
I’m sure there is loads to discuss here, catch up later
The numbers are good. If you go & look at some post hoc analysis...
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