Multisystem Inflammatory Syndrome in U.S. Children and Adolescents
“Cardiovascular involvement was common, with almost half receiving vasopressor or vasoactive support and 1 in 12 having coronary-artery aneurysms. Most patients were cared for in an intensive care unit, and 20% received invasive mechanical ventilator support. Although most discharged patients survived, 28% were still hospitalized as of May 20, 2020, and 4 patients (2%) died, 2 of whom had previously been healthy. “
NEJM June 29, 2020.
186 children, 20% ventilator support
https://www.nejm.org/doi/full/10.1056/NEJMoa2021680?query=C19&cid=DM94780_NEJM_Registered_Users_and_InActive&bid=222925854
anyone who thinks this won’t move Meso tonight, doesn’t have a child directly in the firing line of this virus. The numbers may be small (likely some under reporting/under recognition) but clearly very worrying.
Ann: EAP for Remestemcel-L in Children with MIS-C due to COVID-19, page-126
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