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Was doing some digging around. Thought this was a good article...

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    Was doing some digging around. Thought this was a good article on 2nd line NSCLC after failure of immunotherapy in 1st line.

    Current options for these 2nd line patients:

    (1) doublet chemo if patient received PD-1 monotherapy in 1st line
    (2) single agent chemo if patient received PD-1 + chemo combo in 1st line
    (3) get the patient into a clinical trial

    High unmet need. Described as the "holy grail" in the article.

    https://www.medpagetoday.com/clinical-challenges/asco-thoracic-cancer/87279

 
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