Ann: Emyria Receives Ethics Approval for MDMA-assisted Therapy, page-6

For when lollies shows up =)

"According to the 2007 National Survey of Mental Health and Wellbeing, an estimated 12% of Australians experience PTSD in their life.
"https://www.aihw.gov.au/reports/mental-health-services/stress-and-trauma

"Primary efficacy evaluation of six MAPS-sponsored phase 2 trials on change from Baseline to Primary Endpoint in CAPS-IV Total Severity indicated a significant effect of MDMA over the comparator group (p < 0.001), with a large between-group effect size (0.9 Cohen’s d effect size) that was approximately double that of paroxetine (0.45–0.56) and triple that of sertraline (0.31–0.37). In comparison of mean change in CAPS total scores, placebo subtracted scores for sertraline ranged from 6.8–9.8 units, for paroxetine 6–14 units, and for MDMA 26.2 units (Table 3). The fact that the control group in MDMA studies received the same intensive psychotherapy as the active dose group adds to the clinical significance of these differences."
https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00650/full

MDMA vs Prolonged exposure therapy.
"Effect sizes were calculated for primary and secondary outcome measures in the MDMA-AP clinical trials and compared to those of a meta-analysis including several PE clinical trials. It was found that MDMA-AP had larger effect sizes in both clinician-observed outcomes than PE did (Hedges' g=1.17 vs. g=1.08, respectively) and patient self-report outcomes (Hedges' g=0.87 vs. g=0.77, respectively)."
https://pubmed.ncbi.nlm.nih.gov/27118529/

Long term
" PTSD symptoms were reduced 1 to 2 months after MDMA-assisted psychotherapy, and symptom improvement continued at least 12 months post-treatment. Phase 3 trials are investigating this novel treatment approach in a larger sample of participants with chronic PTSD."
https://pubmed.ncbi.nlm.nih.gov/32500209/

I hold EMD because philosophically I believe in what it's doing as the consequences of severe PTSD can be life destroying. If the company failed but furthered this treatment and resolved PTSD symptoms for people I would still be happy. However, they intend to commercialise this, and they are best positioned to end up with sole rights to analogues which end up more efficacious. If from MDMA assisted psychotherapy they managed to earn 100$ ea from treating 1% of the population a year thats 20 million a year alone.

The market cap is still sub 50m. Don't forget, this is a treatment which has so far demonstrated that it is more effective to what is presently available, treating a common condition which is severely debilitating and has a high social and economic cost - EMD now has the approval to go ahead and produce evidence - and if you can demonstrate evidence that you have a treatment with the best outcomes there aren't many reasons to not do what is best for people affected by PTSD. The fact that they have RX5,7 and are going to do psilocybin assisted therapy are just bonuses.