Ann: Exclusive Supply Agreement with 4C Medical, page-3

Approximately 7 million people in the U.S., suffer from mitral regurgitation in the U.S., and they represent almost 2% of the nation's population. Similarly, approximately the same number of people suffer from the condition in Europe. This group includes 4.1 million people who have moderate to severe mitral regurgitation. The number of new patients suffering with mitral regurgitation disease added each year is 250,000. Among this 4.1 million patients, only about 20% or 1.67 million are eligible for the treatment. This creates huge opportunity for the global transcatheter mitral valve replacement market.

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