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Hi @RaceOncologyQ1. Is 5x the IC50 to get good inhibition of the...

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    Hi @RaceOncology

    Q1. Is 5x the IC50 to get good inhibition of the target enzyme a widely used rule of thumb in pharmacokinetics?

    Q2. So for Zantrene it's 713 nM?
    Comment: 713 nM is equivalent to about 6.3 mg/m2 in a adult.
 
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