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  IN THE JOURNALSPERSPECTIVE
  Smartphone recordings of coughs accurately diagnose respiratory conditions
  
  Porter P, et al. Respir Res. 2019;doi:10.1186/s12931-019-1046-6.
  June 20, 2019
  
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  Paul Porter, MBBS, FRACP , adjunct associate professor in the faculty of health science at Curtin University in Australia, told Infectious Diseases in Children that physicians face numerous challenges diagnosing children with symptoms of respiratory disease.
  
  “Wheezy conditions can include asthma, bronchiolitis, pneumonitis and atypical or viral pneumonia,” he said. “To work these out requires expertise, experience and differential treatment.”
  
  To develop the app, Porter and colleagues recorded cough sounds from 585 children aged 29 days to 12 years in typical clinical environments using a smartphone’s microphone. They developed a diagnostic algorithm that incorporated the cough sounds with five patient- or parent-reported symptoms, including the presence or absence of fever, rhinorrhea, audible wheeze (not stridor), hoarse voice and maximum days of symptoms.
  
  “The objective was to compare diagnoses made by the algorithm to those from a clinical adjudication panel (who had access to all medical records and diagnostic support service results) in order to determine positive and negative percent agreement for a number of respiratory conditions,” the researchers wrote.
  
  Porter said that for 30% of participants whose coughs were recorded, the expert clinicians on the consensus panel — who were “very experienced consultant pediatricians” — disagreed with each other over the diagnosis, showing just how difficult respiratory disease is to diagnose, even with a thorough exam, detailed history and the results of therapeutic testing.
  
  According to the study, the positive percent agreement and negative percent agreement values between the cough analyzer and the clinical reference were 97% and 91% for asthma, 87% and 85% for pneumonia, 83% and 82% for lower respiratory tract disease, 85% and 82% for croup and 84% and 81% for bronchiolitis.
  
  Porter said the technology is ready to use, but he is hoping that it will become more widely accepted within the medical community.
  
  “We are very keen for this tool to be thoroughly accepted and regarded as a serious medical device, not ‘an app on the app stores,’” he said.
  
  Porter and colleagues applied for FDA approval earlier this year. – by Katherine Bortz
  
  https://www.healio.com/pediatrics/respiratory-infections/news/online/{c1e6beb8-396d-4bb0-9268-043c9ef95525}/smartphone-recordings-of-coughs-accurately-diagnose-respiratory-conditions