I found this particular bit very interesting? because it hits home, "The Agency did note however growing concern around the use of chronic opioids in opioid-naive patients and that access to the opioid-naive population may require further specific justification"
My wife happens to be Opioid Naive, she actually had a code blue on a self administered morphine injection some years ago which was supposedly safe? she has recently had another operation where opioids were administered even after I told them she had problems with any opioid drug, in their wisdom they gave it to her anyway? and I am now suffering some of the consequences of that decision!
Some of our medical system sucks, but that is a whole new thing which is unrelated here in some ways, so I won't go on!
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Ann: FDA meeting provides guidance for TPM/Oxymorphone patch, page-8
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