Ann: FIH Results Presented at EuroPCR & Simultaneous Publication, page-12

7 new patients.... they directly reference 48hr post-procedure haemodynamics...

In parallel to the publication, an expanded FIH data set incorporating post-procedural data for an
additional seven recently enrolled patients was presented by Dr Susheel Kodali during a scientific
session at EuroPCR 2023.

Post-procedure Haemodynamics (48hr TTE)

• Increased average Effective Orifice Area (EOA) by 307% from baseline – an indicator of
increased long-term survival and exercise capacity.

• Reduced mean pressure gradient (MPG) across the valve by 84% from baseline.