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Ann: Final Phase IIb AIPAC clinical trial results for Efti in MBC, page-74

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    Some points from the presentation.

    Significant deterioration of QoL (QLQ-C30-B23) observed in the
    placebo group at 6 months. No deterioration with efti (Figure 6).

    • Efti significantly increased CD8 T cells compared to placebo
    (Figure 7). (Note: Blood samples were taken 2 weeks after last dosing and prior to
    next dosing, showing the minimal residual effect.)

    • Increase in pre-dose CD8 T cells is significantly correlated to
    increased overall survival (Figure 8).
 
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