Ann: First Patient of Cohort 2 Dosed in MND Trial, page-41

All good this end Beefy.

Yes Positive Results with the Dose escalation could bring significant awareness of PAA. Fight MND should be able to gain some serious media which also encourages further donations to the cause.

This MND Trial is really to discover enough PKD data to enable the Human Covid and Human Cancer Trials to progress.( The Trial is fully funded by Fight MND)

MPL which is the key drug PAA are working on has shown Truly Remarkable results against SARs1 and SARs 2 based Virus.
Double Tested at the Walter and Eliza Hall Institute demonstrated a Viral load reduction of 99% with in a 72 hour exposure to MPL.
This was confirmed again by Biolabs 360 and then By Leiden University in Holland.

Company is underfunded but has been steadfast on not diluting SH equity , but as we know "everything has a cost" ..

During Covid the bar was lowered to enable companies to step over it for Interim FDA approval and granting Orphan Drug Status for anything that could be thrown at Covid.. company did not strike at the opportunity or seek any of the Govt funding ,some of our other holdings benefitted from jumping on the Govt Grant band wagon..

Phase II Human Cancer Trial was suspended in 2017 so the company could manufacture a Palatable Tablet, this has now been completed.
Sufficient data was obtained to permit proceeding to Phase II study, i.e. a safe and active dose. The study was also terminated to permit reformulation of study drug to a more palatable formulation

There are only two other mTOR Pathway Drugs that have been commercialised , between them they have shared a market value of $2.4B,, MPL has not shown any adverse effects unlike the 2 incumbents , one of which is Pfizer... So I see PAA would have considerable value to Pfizer.

Company has really struggled in the past to impart Commercial Value alongside Scientific Progress but late last year the Company began to remedy this.

There are roughly $14m worth of oppies that could be struck before October and that would provide a cash runway to complete Human and Covid trials .

Great to see our other stock making us some money..... NZT