Dr Sud's characterisation of what makes a drug candidate...

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malkazoid

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03/06/22

10:28

Post #: 61797895
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Originally posted by FreeBobby2002: ↑

Question from me - per page 12- average AHI baseline is 42.8 which is well within the "Severe" category.

All 3 dosage levels have transitioned the subject from the "Severe" to "Moderate" level. But not quite into Mild or Minimal.

Is this an issue - What is a realistic "end" AHI level for CPAP? Is this achieved via using the machine for a longer period of time?

That being said - perhaps we should not be looking at IHL-42x as a "silver bullet" so to speak which cures sleep apnea completely - but something that can reliably improve AHI levels and thus, quality of life and obviously burden on the healthcare system.

AHI levels:
None/Minimal: AHI < 5 per hour
Mild: AHI ≥ 5, but < 15 per hour
Moderate: AHI ≥ 15, but < 30 per hour
Severe: AHI ≥ 30 per hour

Source:
https://cpapsupplies.com/blog/what-is-ahi-in-relation-to-sleep-apnea#:~:text=What%20Is%20the%20Goal%20AHI,ideal%2C%20any%20improvement%20is%20beneficial.

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Dr Sud's characterisation of what makes a drug candidate valuable: 10 to 15 percent efficacy. We are way, WAY beyond.
As you suggest, rather than a cure, I think that's the benchmark to keep in mind.

IHL Price at posting: 41.5¢ Sentiment: Buy Disclosure: Held
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Dr Sud's characterisation of what makes a drug candidate...

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