JIA is the most common type of arthritis in children. It affects about 1 in 1,000 children, or about 300,000 children in the United States. It is a long lasting disease.
From the study mentioned in the announcement... sounds promising.
Results:In patients with o-JIA, soluble levels of LAG-3 and expression of LAG-3 and T cell immunoglobulin mucin03 (TIM-3) on CD3+CD4+CD45RO+T cells were increased, especially in SF. Major histocompatibility complex (MHC) class II expression was induced on FLSs when these were co-cultured with autologous PBMCs/SFMCs, together with an increased monocyte chemoattractant protein-1 (MCP-1) production. In PBMC and FLS + PBMC co-cultures, neutralizing antibodies to IRs were added. Only anti-LAG-3 antibodies significantly increased MCP-1 secretion. The addition of agonistic LAG-3 antibody resulted in decreased effector cytokine secretion.
https://pubmed.ncbi.nlm.nih.gov/34031570/
- Forums
- ASX - By Stock
- Ann: Immutep Advances IMP761 Manufacturing
JIA is the most common type of arthritis in children. It affects...
Featured News
Add IMM (ASX) to my watchlist
|
|||||
Last
32.0¢ |
Change
0.015(4.92%) |
Mkt cap ! $464.8M |
Open | High | Low | Value | Volume |
30.0¢ | 32.5¢ | 30.0¢ | $1.168M | 3.702M |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
5 | 148547 | 32.0¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
32.5¢ | 51809 | 2 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
5 | 148547 | 0.320 |
3 | 107807 | 0.315 |
2 | 38192 | 0.310 |
2 | 58192 | 0.305 |
10 | 490669 | 0.300 |
Price($) | Vol. | No. |
---|---|---|
0.325 | 44309 | 1 |
0.330 | 179497 | 6 |
0.335 | 82304 | 5 |
0.340 | 49303 | 3 |
0.345 | 27527 | 3 |
Last trade - 16.10pm 24/07/2024 (20 minute delay) ? |
Featured News
IMM (ASX) Chart |
The Watchlist
1CG
ONE CLICK GROUP LIMITED
Mark Waller, MD
Mark Waller
MD
Previous Video
Next Video
SPONSORED BY The Market Online