https://www.estrellabio.com/technology
The Mark-and-Kill ApproachTo address the issue of the lack of solid tumor-specific targets, we use an oncolytic virus to force solid tumor cells to express the CD19 protein on the cell surface. The CD19-Redirected ARTEMIS T Cells can then pursue and kill the CD19-labeled solid tumors, offering a potential treatment solution to cancers where there are no inherently abundant solid tumor-specific targets available.
Ann: Imugene onCARlytics with Estrella ARTEMIS T Cells SITC, page-6
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