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Ann: Imugene PD1-Vaxx Update, page-113

  1. 611 Posts.
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    Thanks for your response from IMU, nice to hear it.
    I also got a response from Nick Ede.
    The cause of the Pneumonitis May or may not be from PD1 Vaxx.
    . It certainly happens with ICI’s , and chemo. ( seems up to 20%)
    Thats why we need phase 2 trials , to compare .
    And yes, “others” do seem to express different views to oncologists. ( and can remain anonymous)


    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888158/

    “Risk factors for pneumonitis in patients with non‐small cell lung cancer treated with immune checkpoint inhibitors plus chemotherapy: A retrospective analysis - PMCThis study revealed that pre‐existing ILD is a risk factor for pneumonitis induced by ICI therapy and chemotherapy in patients with NSCLC. In phase III clinical trials, the incidence of pneumonitis in patients with NSCLC treated with PD‐1 inhibitor monotherapy was reported to be approximately 3%–6%. 1 , 2 , 3 , 4 , 5 On the contrary, according to reports based on real‐world data, the incidence rate of ICI‐induced pneumonitis tended to be high at approximately 10%–20%. 11 , 12 , 13 , 14 “
 
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