Share
11,435 Posts.
lightbulb Created with Sketch. 508
clock Created with Sketch. 20/04/20
11:38
Share
Originally posted by bedger
↑
So correct me if I am wrong, but essentially people with severe COVID-19 die from ARDS (acute respiratory distress syndrome). Diseases such as covid-19 and influenza can be fatal due to an overreaction of the body’s immune system called a cytokine storm. Cytokines (small proteins) are released by the immune system. The body’s response to infection goes into overdrive. When COVID-19 enters the lungs, it triggers an immune response, attracting immune cells to the region to attack the virus, resulting in localised inflammation. Excessive or uncontrolled levels of cytokines are released which then activate more immune cells, resulting in hyper-inflammation. This is the infection that literally sits on your alveolus (tiny membranes at the end of your lungs that pass oxygen into your bloodstream) literally drowning patients as they cannot get oxygen through to the bloodstream as their alveolus are massively inflamed impeding the transfer. People get no oxygen to their bloodstream, hence the drowning analogies.
Expand
"Remestemcel-L intravenous infusions have been evaluated in over 1,100 patients in various clinical trials mainly in relation to acute graft versus host disease (aGVHD) in children".
(20min delay)